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Click Here for Indications VIVITROL is indicated for:
  • The treatment of alcohol dependence in patients who are able to abstain from alcohol in an outpatient setting prior to initiation of treatment with VIVITROL. Patients should not be actively drinking at the time of initial VIVITROL administration.
  • The prevention of relapse to opioid dependence, following opioid detoxification.

VIVITROL should be part of a comprehensive management program that includes psychosocial support.


Storage of VIVITROL1

VIVITROL is supplied in cartons (NDC 65757-300-01). Each carton contains:

  • one 380 mg vial of VIVITROL microspheres in a 5-mL single-dose vial,
  • one vial containing 4 mL of diluent (to deliver 3.4 mL) for the suspension of VIVITROL,
  • one 5-mL prepackaged syringe,
  • one 20-gauge 1-inch needle,
  • two 20-gauge 1 1/2-inch needles with needle protection devices, and;
  • two 20-gauge 2-inch needles with needle protection devices

VIVITROL must be prepared and administered by a healthcare provider.

The entire dose pack should be stored in the refrigerator (2 °C to 8 °C, 36 °F to 46 °F).
Unrefrigerated, VIVITROL can be stored at temperatures not exceeding 25 °C (77 °F) for no more than 7 days prior to administration. Do not expose the product to temperatures above 25 °C (77 °F). VIVITROL should not be frozen.

Keep out of Reach of Children.

Each carton of VIVITROL includes1:

Items included in each carton of VIVITROL®

One – Package Insert/Directions for Use

One – Medication Guide

  1. One – Diluent for the suspension of VIVITROL Microspheres
  2. One – Vial containing VIVITROL Microspheres
  3. One – Prepackaged Syringe
  4. Two – TERUMO® 1 1/2 inch 20G Administration Needles with clear Needle
    Protection Device [one spare]
  5. Two – TERUMO® 2-inch 20G Administration Needles with clear Needle
    Protection Device [one spare]
  6. One – TERUMO® 1-inch 20G Preparation Needle [Not for Administration]

Parenteral products should be visually inspected for particulate matter and discoloration prior to administration.

The carton should not be exposed to temperatures exceeding 25 °C (77 °F)

The entire carton should be stored in the refrigerator (2 °C to 8 °C, 36 °F to 46 °F). Unrefrigerated, VIVITROL microspheres can be stored at temperatures not exceeding 25 °C (77 °F) for no more than 7 days prior to administration. Do not expose unrefrigerated product to temperatures above 25 °C (77 °F). VIVITROL should not be frozen.

See section 2.6 Prescribing Information for complete directions for use.

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Reference: 1. VIVITROL [prescribing information]. Waltham, MA: Alkermes, Inc; rev March 2021.

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Reference: 1. VIVITROL [prescribing information]. Waltham, MA: Alkermes, Inc; rev March 2021.

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